Dr. János Benyeda and his wife started their entrepreneurial work by pre-hatching fertile hen eggs, which they delivered to Phylaxia Vaccine Production Company, the predecessor of Ceva.
Soon, they started producing virus and immune serum to be used as raw material for veterinary vaccines. They developed a swine fever virus in rabbits, the LaSota strain of avian influenza virus in embryonated hen eggs, and a serum against Derzhy’s disease in geese for the vaccine producer.
Prophyl Animal Health, Diagnostics, Research and Services LLC was founded in 1991. In the same year, the couple also opened a veterinary clinic and started to carry out tests commissioned by Phylaxia that became necessary in the course of quality control, registration or research and development of vaccines.
In the meantime, they established their own broods for the production of fertile eggs for vaccines, as well as on-site facilities for processing and pre-hatching eggs.
In 2000, the company's first SPF egg production plant was established. Since then, the company, in partnership with Charles River Laboratories of the US, has become one of Europe's leading producers of SPF eggs, with 3 SPF sites.
In parallel with this, utilising decades of experience in animal testing, they established Hungary’s largest integrated livestock testing facility in vaccine research and development, which is also recognised as a major testing base in the EU. The GLP (good laboratory practice) certified testing facility has animal houses of various biosafety levels. Animal houses with the highest safety level are BSL-3 containment facilities.
2018 saw the handover of a complex diagnostic laboratory unit and a site-specific vaccine production laboratory. This is where the vaccine is produced that was first developed in the 2000s in collaboration with Dr. Vilmos Palya for the prevention of haemorrhagic enteritis and nephrolithiasis in geese. The studies carried out during the development of the vaccine have contributed greatly to a better understanding of the pathology and epidemiology of the disease caused by the polyoma virus.